Geraniin extracted from the rind of Nephelium lappaceum binds to dengue virus type-2 envelope protein and inhibits early stage of virus replication

Geraniin extracted from the rind of Nephelium lappaceum binds to dengue virus type-2 envelope protein and inhibits early stage of virus replication

Abstract Background The rapid rise and spread in dengue cases, together with the unavailability of safe vaccines and effective antiviral drugs, warrant the need to discover and develop novel anti-dengue treatments. In this study the antiviral activity of geraniin, extracted from the rind of Nepheliu...

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Bibliographic Details
Main Authors: Siti Aisyah Abdul Ahmad, Uma D. Palanisamy, Bimo A. Tejo, Miaw Fang Chew, Hong Wai Tham, Sharifah Syed Hassan
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Virology Journal
Subjects:
Antiviral
DENV-2 E protein
Geraniin
Nephelium lappaceum
Online Access:http://link.springer.com/article/10.1186/s12985-017-0895-1

Internet

http://link.springer.com/article/10.1186/s12985-017-0895-1

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