In vitro and in vivo analysis of monotherapy and dual therapy with ethyl caffeate and fluconazole on virulence factors of Candida albicans and systemic candidiasis

In vitro and in vivo analysis of monotherapy and dual therapy with ethyl caffeate and fluconazole on virulence factors of Candida albicans and systemic candidiasis

ABSTRACT: Objectives: Candida albicans is the most clinically prevalent cause of systemic fungal infections in the immunocompromised population. The biofilm-forming ability of C. albicans confers resistance to conventional antifungal agents. The main aim of this study was to investigate the antifun...

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Bibliographic Details
Main Authors: Tianming Wang, Min Pan, Nan Xiao, Jiadi Wu, Qirui Wang, Ting Cheng, Guiming Yan, Daqiang Wu, Ning Li, Jing Shao
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Journal of Global Antimicrobial Resistance
Subjects:
Candida albicans
Ethyl caffeate
Fluconazole
Fungal infection
Combination
Synergy
Online Access:http://www.sciencedirect.com/science/article/pii/S2213716521002204

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http://www.sciencedirect.com/science/article/pii/S2213716521002204

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