Shared Genetic Etiology of Primary Dilated Cardiomyopathy and Ischemic Dilated Cardiomyopathy

Shared Genetic Etiology of Primary Dilated Cardiomyopathy and Ischemic Dilated Cardiomyopathy

Background: Mutations in genes encoding sarcomere and cytoskeletal proteins are major causes of primary dilated cardiomyopathy (DCM). Likewise, ischemic myocardial injury is a major cause of secondary cardiac remodeling, which, in a subset, is severe and resembles DCM. The latter is referred to as i...

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Bibliographic Details
Main Authors: Yang Sun, Lei Xiao, Ke Li, Hong Wang, Xiuli Song, Zongzhe Li, Chenze Li, Yanghui Chen, Shiyang Li, Jin Huang, Lun Tan, Dong Hu, Ting Yu, Rui Li, Li Jin, Leming Shi, Ali J. Marian, Dao Wen Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
dilated cardiomyopathy
ischemic cardiomyopathy
TTN
whole-exome sequencing
ACMG classification
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2021.752662/full

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https://www.frontiersin.org/articles/10.3389/fcvm.2021.752662/full

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