Combination of Genetics and Nanotechnology for Down Syndrome Modification: A Potential Hypothesis and Review of the Literature

Combination of Genetics and Nanotechnology for Down Syndrome Modification: A Potential Hypothesis and Review of the Literature

Down syndrome (DS) is one of the most prevalent genetic disorders in humans. The use of new approaches in genetic engineering and nanotechnology methods in combination with natural cellular phenomenon can modify the disease in affected people. We consider two CRISPR/Cas9 systems to cut a specific re...

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Bibliographic Details
Main Authors: Alireza TAFAZOLI, Farkhondeh BEHJATI, Dariush D. FARHUD, Mohammad Reza ABBASZADEGAN
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2019-03-01
Series:Iranian Journal of Public Health
Subjects:
Down syndrome
CRISPR/Cas9
Designed DNA construct
Poly D L-lactide-co-glycolide (PLGA)
Nano-carrier
Chromosome 21 inactivation
Online Access:https://ijph.tums.ac.ir/index.php/ijph/article/view/16505

Internet

https://ijph.tums.ac.ir/index.php/ijph/article/view/16505

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