Identification of bioactive compounds and potential mechanisms of scutellariae radix-coptidis rhizoma in the treatment of atherosclerosis by integrating network pharmacology and experimental validation

Identification of bioactive compounds and potential mechanisms of scutellariae radix-coptidis rhizoma in the treatment of atherosclerosis by integrating network pharmacology and experimental validation

Objective: This study aims at investigating the potential targets and functional mechanisms of Scutellariae Radix-Coptidis Rhizoma (QLYD) against atherosclerosis (AS) through network pharmacology, molecular docking, bioinformatic analysis and experimental validation. Methods: The compositions of QLY...

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Bibliographic Details
Main Authors: Lingyun Ji, Ting Song, Chunlei Ge, Qiaolan Wu, Lanying Ma, Xiubao Chen, Ting Chen, Qian Chen, Zetao Chen, Weida Chen
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Scutellariae radix-coptidis rhizoma
Atherosclerosis
Network pharmacology
Molecular docking techniques
Bioinformatics
Mechanism
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223010016

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http://www.sciencedirect.com/science/article/pii/S0753332223010016

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