Propranolol Suppresses the T-Helper Cell Depletion-Related Immune Dysfunction in Cirrhotic Mice

Propranolol Suppresses the T-Helper Cell Depletion-Related Immune Dysfunction in Cirrhotic Mice

Bacterial translocation (BT) and splenomegaly contribute to cirrhosis-associated immune dysfunction (CAID) including T cell depletion, infection, and chronic inflammation. β-blockers have been reported to decrease BT and improve splenomegaly. This study explores the modulation of β...

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Bibliographic Details
Main Authors: Hung-Cheng Tsai, Chien-Fu Hsu, Chia-Chang Huang, Shiang-Fen Huang, Tzu-Hao Li, Ying-Ying Yang, Ming-Wei Lin, Tzung-Yan Lee, Chih-Wei Liu, Yi-Hsiang Huang, Ming-Chih Hou, Han-Chieh Lin
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cells
Subjects:
cirrhosis-associated immune dysfunction
splenic β adrenergic receptor
th-cell depletion
Online Access:https://www.mdpi.com/2073-4409/9/3/604

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https://www.mdpi.com/2073-4409/9/3/604

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