DNA Minicircle Technology Improves Purity of Adeno-associated Viral Vector Preparations

DNA Minicircle Technology Improves Purity of Adeno-associated Viral Vector Preparations

Adeno-associated viral (AAV) vectors are considered as one of the most promising delivery systems in human gene therapy. In addition, AAV vectors are frequently applied tools in preclinical and basic research. Despite this success, manufacturing pure AAV vector preparations remains a difficult task....

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Bibliographic Details
Main Authors: Maria Schnödt, Marco Schmeer, Barbara Kracher, Christa Krüsemann, Laura Escalona Espinosa, Anja Grünert, Thomas Fuchsluger, Anja Rischmüller, Martin Schleef, Hildegard Büning
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
AAV vectors
DNA impurities
Minicircle
Vector production
Vector quality
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253117300744

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http://www.sciencedirect.com/science/article/pii/S2162253117300744

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