Nano-encapsulated tanshinone IIA in PLGA-PEG-COOH inhibits apoptosis and inflammation in cerebral ischemia/reperfusion injury

Nano-encapsulated tanshinone IIA in PLGA-PEG-COOH inhibits apoptosis and inflammation in cerebral ischemia/reperfusion injury

Tanshinone IIA has a potential therapeutic effect on cerebral ischemia/reperfusion injury (CIRI). In this study, tanshinone IIA was encapsulated in poly(lactic-co-glycolic acid)-block-poly (ethylene glycol)-carboxylic acid (PLGA-PEG-COOH) nanoparticles, and its therapeutic efficacy on CIRI was inves...

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Bibliographic Details
Main Authors: Zhang Xin, Zhu Xutong, Huang Lifa, Chen Zupeng, Wang Yuchen, Liu Yajun, Pan Ruihan, Lv Ling
Format: Article
Language:English
Published: De Gruyter 2023-03-01
Series:Green Processing and Synthesis
Subjects:
plga-peg-cooh nanoparticles
tanshinone iia
cerebral ischemia/reperfusion injury
angiopep-2 peptide
blood–brain barrier
Online Access:https://doi.org/10.1515/gps-2022-8156

Internet

https://doi.org/10.1515/gps-2022-8156

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