Side-by-side comparison of G-quadruplex (G4) capture efficiency of the antibody BG4 versus the small-molecule ligands TASQs

Summary: The search for G-quadruplex (G4)-forming sequences across the genome is motivated by their involvement in key cellular processes and their putative roles in dysregulations underlying human genetic diseases. Sequencing-based methods have been developed to assess the prevalence of DNA G4s gen...

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Bibliographic Details
Main Authors: Yilong Feng, Zexue He, Zhenyu Luo, Francesco Rota Sperti, Ibai E. Valverde, Wenli Zhang, David Monchaud
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223009239