Liquid chromatography coupled to high-resolution mass spectrometry metabolomics: A useful tool for investigating tumor secretome based on a three-dimensional co-culture model

Three-dimensional (3D) cell culture technologies, which more closely mimic the complex microenvironment of tissue, are being increasingly evaluated as a tool for the preclinical screening of clinically promising new molecules, and studying of tissue metabolism. Studies of metabolites released into t...

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Bibliographic Details
Main Authors: Andrea C. Pelosi, Anna Maria A. P. Fernandes, Leonardo F. Maciel, Alex A. R. Silva, Giulia C. Mendes, Luísa F. Bueno, Lívia Maria F. Silva, Rafael F. Bredariol, Maycon G. Santana, Andreia M. Porcari, Denise G. Priolli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9491614/?tool=EBI