Single nucleotide polymorphisms in A4GALT spur extra products of the human Gb3/CD77 synthase and underlie the P1PK blood group system.

Contrary to the mainstream blood group systems, P1PK continues to puzzle and generate controversies over its molecular background. The P1PK system comprises three glycosphingolipid antigens: Pk, P1 and NOR, all synthesised by a glycosyltransferase called Gb3/CD77 synthase. The Pk antigen is present...

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Bibliographic Details
Main Authors: Radoslaw Kaczmarek, Katarzyna Szymczak-Kulus, Anna Bereźnicka, Krzysztof Mikołajczyk, Maria Duk, Edyta Majorczyk, Anna Krop-Watorek, Elżbieta Klausa, Joanna Skowrońska, Bogumiła Michalewska, Ewa Brojer, Marcin Czerwinski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5927444?pdf=render