NK1-r Antagonist Treatment Comparable to Decompressive Craniectomy in Reducing Intracranial Pressure Following Stroke

NK1-r Antagonist Treatment Comparable to Decompressive Craniectomy in Reducing Intracranial Pressure Following Stroke

Background and Purpose: The morbidity and early mortality associated with stroke is largely attributable to cerebral edema and elevated intracranial pressure (ICP). Existing pharmacotherapies do not target the underlying pathophysiology and are often ineffective in sustainably lowering ICP, whilst d...

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Bibliographic Details
Main Authors: Annabel J. Sorby-Adams, Anna V. Leonard, Jan W. Hoving, Nawaf Yassi, Robert Vink, Adam J. Wells, Renée J. Turner
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Neuroscience
Subjects:
intracranial pressure
cerebral edema
substance P
decompressive craniectomy
blood-brain barrier
stroke
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.00681/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2019.00681/full

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