AGO unchained: Canonical and non-canonical roles of Argonaute proteins in mammals

Argonaute (AGO) proteins play key roles in animal physiology by binding to small RNAs and regulating the expression of their targets. In mammals, they do so through two distinct pathways: the miRNA pathway represses genes through a multiprotein complex that promotes both decay and translational repr...

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Bibliographic Details
Main Authors: Laura Sala, Srividya Chandrasekhar, Joana A. Vidigal
Format: Article
Language:English
Published: IMR Press 2020-01-01
Series:Frontiers in Bioscience-Landmark
Subjects:
Online Access:https://www.imrpress.com/journal/FBL/25/1/10.2741/4793