Cohort-Specific Peptide Reagents Broaden Depth and Breadth Estimates of the CD8 T Cell Response to HIV-1 Gag Potential T Cell Epitopes

Cohort-Specific Peptide Reagents Broaden Depth and Breadth Estimates of the CD8 T Cell Response to HIV-1 Gag Potential T Cell Epitopes

An effective HIV vaccine will need to stimulate immune responses against the sequence diversity presented in circulating virus strains. In this study, we evaluate breadth and depth estimates of potential T-cell epitopes (PTEs) in transmitted founder virus sequence-derived cohort-specific peptide rea...

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Bibliographic Details
Main Authors: Clive M. Michelo, Andrew Fiore-Gartland, Jama A. Dalel, Peter Hayes, Jianming Tang, Edward McGowan, William Kilembe, Natalia Fernandez, Jill Gilmour, Eric Hunter
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Vaccines
Subjects:
CD8 T-cell
epitope-mapping
HIV-1
HIV-1 vaccine
Online Access:https://www.mdpi.com/2076-393X/11/2/472

Internet

https://www.mdpi.com/2076-393X/11/2/472

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