Cytokine Responses during <i>Mycobacterium tuberculosis</i> H37Rv and <i>Ascaris lumbricoides</i> Costimulation Using Human THP-1 and Jurkat Cells, and a Pilot Human Tuberculosis and Helminth Coinfection Study

Cytokine Responses during <i>Mycobacterium tuberculosis</i> H37Rv and <i>Ascaris lumbricoides</i> Costimulation Using Human THP-1 and Jurkat Cells, and a Pilot Human Tuberculosis and Helminth Coinfection Study

Background: Helminth infections are widespread in tuberculosis-endemic areas and are associated with an increased risk of active tuberculosis. In contrast to the pro-inflammatory Th1 responses elicited by <i>Mycobacterium tuberculosis</i> (Mtb) infection, helminth infections induce anti-...

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Bibliographic Details
Main Authors: Khethiwe N. Bhengu, Ravesh Singh, Pragalathan Naidoo, Miranda N. Mpaka-Mbatha, Nomzamo Nembe-Mafa, Zilungile L. Mkhize-Kwitshana
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Microorganisms
Subjects:
<i>Mycobacterium tuberculosis</i> H37Rv
<i>Ascaris lumbricoides</i> excretory-secretory proteins
Jurkat cells
THP-1 cells
human tuberculosis and helminth co-infection
cytokine gene transcription levels
Online Access:https://www.mdpi.com/2076-2607/11/7/1846

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https://www.mdpi.com/2076-2607/11/7/1846

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