A high-throughput method for exploring the parameter space of protein liquid-liquid phase separation

Summary: Numerous proteins can undergo liquid-liquid phase separation (LLPS) in various biological processes. However, it remains a challenge to systematically evaluate the LLPS ability of proteins. Here, we develop a high-throughput protein phase separation (HiPPS) profiling method to delineate LLP...

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Bibliographic Details
Main Authors: Yichen Li, Jinge Gu, Cong Liu, Dan Li
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:Cell Reports Physical Science
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666386422000315