Population pharmacokinetics in critically ill neonates and infants undergoing extracorporeal membrane oxygenation: a literature review

Extracorporeal membrane oxygenation (ECMO) increases circulating blood volume, causes capillary leak and temporarily alters kidney function. Consequently, pharmacokinetics (PK) can be affected. When applied to neonates and infants, additional dose adjustments are a major concern, as the volume of di...

Full description

Bibliographic Details
Main Authors: Karel Allegaert, Nadir Yalcin, Nursel Sürmelioğlu
Format: Article
Language:English
Published: BMJ Publishing Group 2022-11-01
Series:BMJ Paediatrics Open
Online Access:https://bmjpaedsopen.bmj.com/content/6/1/e001512.full