Population pharmacokinetics in critically ill neonates and infants undergoing extracorporeal membrane oxygenation: a literature review
Extracorporeal membrane oxygenation (ECMO) increases circulating blood volume, causes capillary leak and temporarily alters kidney function. Consequently, pharmacokinetics (PK) can be affected. When applied to neonates and infants, additional dose adjustments are a major concern, as the volume of di...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMJ Publishing Group
2022-11-01
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Series: | BMJ Paediatrics Open |
Online Access: | https://bmjpaedsopen.bmj.com/content/6/1/e001512.full |