GGC Repeat Expansion in the NOTCH2NLC Gene Is Associated With a Phenotype of Predominant Motor–Sensory and Autonomic Neuropathy

GGC Repeat Expansion in the NOTCH2NLC Gene Is Associated With a Phenotype of Predominant Motor–Sensory and Autonomic Neuropathy

There is still a considerable proportion of patients with inherited peripheral neuropathy (IPN) whose pathogenic genes are unknown. This study was intended to investigate whether the GGC repeat expansion in the NOTCH2NLC is presented in some patients with IPN. A total of 142 unrelated mainland Chine...

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Bibliographic Details
Main Authors: Hui Wang, Jiaxi Yu, Meng Yu, Jianwen Deng, Wei Zhang, He Lv, Jing Liu, Xin Shi, Wei Liang, Zhirong Jia, Daojun Hong, Lingchao Meng, Zhaoxia Wang, Yun Yuan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Genetics
Subjects:
inherited peripheral neuropathy
motor–sensory and autonomic neuropathy
NOTCH2NLC
GGC repeat expansions
NOTCH2NLC-related repeat expansion spectrum
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.694790/full

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https://www.frontiersin.org/articles/10.3389/fgene.2021.694790/full

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