Antidepressants as a potential candidate to reduce microglia activation in neurodegenerative diseases. A systematic review and meta-analysis of preclinical studies

There is special interest in antidepressants as potential repurposing drugs for neurodegenerative disorders (ND). Microglia activation is implicated to play a causal role in the pathogenesis of ND. Furthermore, preclinical studies showed profound impact of antidepressants on microglial cells. Howeve...

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Bibliographic Details
Main Authors: Lisa Nicolai, Pauline Nettesheim, Lot D. de Witte, Gijsje Snijders
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Journal of Affective Disorders Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666915323000045