Chemical inducer of regucalcin attenuates lipopolysaccharide‐induced inflammatory responses in pancreatic MIN6 β‐cells and RAW264.7 macrophages

Chemical inducer of regucalcin attenuates lipopolysaccharide‐induced inflammatory responses in pancreatic MIN6 β‐cells and RAW264.7 macrophages

We previously isolated derrisfolin A, a novel rotenoid derivative, from the stems of Derris trifoliata Lour. (Leguminosae). Here, we report that derrisfolin A induces the expression of endogenous regucalcin (RGN) protein in both pancreatic MIN6 β‐cells and RAW264.7 macrophages. Induction of RGN expr...

Full description

Bibliographic Details
Main Authors: Tomiyasu Murata, Kazunori Hashimoto, Susumu Kohno, Chiaki Takahashi, Masayoshi Yamaguchi, Chihiro Ito, Itoigawa Masataka, Roji Kojima, Kiyomi Hikita, Norio Kaneda
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:FEBS Open Bio
Subjects:
derrisfolin A
inflammation
lipopolysaccharide
MIN6 cells
RAW264.7 macrophages
regucalcin
Online Access:https://doi.org/10.1002/2211-5463.13321

Internet

https://doi.org/10.1002/2211-5463.13321

Similar Items