Pharmacological administration of the isoflavone daidzein enhances cell proliferation and reduces high fat diet-induced apoptosis and gliosis in the rat hippocampus.

Soy extracts have been claimed to be neuroprotective against brain insults, an effect related to the estrogenic properties of isoflavones. However, the effects of individual isoflavones on obesity-induced disruption of adult neurogenesis have not yet been analyzed. In the present study we explore th...

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Main Authors: Patricia Rivera, Margarita Pérez-Martín, Francisco J Pavón, Antonia Serrano, Ana Crespillo, Manuel Cifuentes, María-Dolores López-Ávalos, Jesús M Grondona, Margarita Vida, Pedro Fernández-Llebrez, Fernando Rodríguez de Fonseca, Juan Suárez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23741384/?tool=EBI