N-3 polyunsaturated Fatty acids prevent diabetic retinopathy by inhibition of retinal vascular damage and enhanced endothelial progenitor cell reparative function.

The vasodegenerative phase of diabetic retinopathy is characterized by not only retinal vascular degeneration but also inadequate vascular repair due to compromised bone marrow derived endothelial progenitor cells (EPCs). We propose that n-3 polyunsaturated fatty acid (PUFA) deficiency in diabetes r...

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Bibliographic Details
Main Authors: Maria Tikhonenko, Todd A Lydic, Madalina Opreanu, Sergio Li Calzi, Svetlana Bozack, Kelly M McSorley, Andrew L Sochacki, Matthew S Faber, Sugata Hazra, Shane Duclos, Dennis Guberski, Gavin E Reid, Maria B Grant, Julia V Busik
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3558503?pdf=render