Population analysis of Legionella pneumophila reveals a basis for resistance to complement-mediated killing

The bacterium Legionella pneumophila can cause severe respiratory infection, but is typically a symbiont of free-living amoeba. Here, the authors analyse the genomes of 902 clinical and environmental isolates, and identify a bacterial gene that is strongly associated with human infection and confers...

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Bibliographic Details
Main Authors: Bryan A. Wee, Joana Alves, Diane S. J. Lindsay, Ann-Brit Klatt, Fiona A. Sargison, Ross L. Cameron, Amy Pickering, Jamie Gorzynski, Jukka Corander, Pekka Marttinen, Bastian Opitz, Andrew J. Smith, J. Ross Fitzgerald
Format: Article
Language:English
Published: Nature Portfolio 2021-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-27478-z