Generation of a fluorescent oligodendrocyte reporter line in human induced pluripotent stem cells

Human brain organoids can serve as models to study myelination, a process orchestrated by oligodendrocytes. Real-time imaging provides new insights on the communication of oligodendrocytes with neurons as well as demyelination processes in patient derived organoids. PLP1, a prominent myelin protein...

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Bibliographic Details
Main Authors: Marie-Kristin Schreiber, Maria-Patapia Zafeiriou
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506123002817