Optogenetic activation of UCP1-dependent thermogenesis in brown adipocytes

Optogenetic activation of UCP1-dependent thermogenesis in brown adipocytes

Summary: Brown adipocytes are unique in that they expend energy and produce heat to maintain euthermia through expression of uncoupling protein-1 (UCP1). Given their propensity to stimulate weight loss and promote resistance to obesity, they are a compelling interventional target for obesity-related...

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Bibliographic Details
Main Authors: Chad C. Doucette, Daniel C. Nguyen, Davide Barteselli, Sophia Blanchard, Mason Pelletier, Devesh Kesharwani, Ed Jachimowicz, Su Su, Michele Karolak, Aaron C. Brown
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:iScience
Subjects:
Molecular biology experimental approach
Metabolic engineering
Specialized functions of cells
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223006375

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http://www.sciencedirect.com/science/article/pii/S2589004223006375

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