Overexpression of miR-204-5p Alleviates Osteogenic Differentiation and Calcification of Human Aortic Vascular Smooth Muscle Cells by Targeting Calcium/Calmodulin-dependent Protein Kinase 1

Overexpression of miR-204-5p Alleviates Osteogenic Differentiation and Calcification of Human Aortic Vascular Smooth Muscle Cells by Targeting Calcium/Calmodulin-dependent Protein Kinase 1

Vascular calcification (VC), a major complication in chronic kidney disease (CKD), is predominantly driven by osteoblastic differentiation. Recent studies have highlighted the crucial role of microRNAs in CKD’s pathogenesis. Here, our research focused on the effects of miR-204-5p and its molecular m...

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Bibliographic Details
Main Authors: Chunli Wang, Mingzhi Xu, Yafei Bai, Mingjiao Pan, Yonghui Qi, Ruman Chen
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-03-01
Series:Journal of Physiological Investigation
Subjects:
calmodulin-dependent protein kinase 1
chronic kidney disease
human aortic vascular smooth muscle cells
mir-204-5p
vascular calcification
Online Access:https://journals.lww.com/10.4103/ejpi.EJPI-D-24-00003

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https://journals.lww.com/10.4103/ejpi.EJPI-D-24-00003

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