Driving-pressure-independent protective effects of open lung approach against experimental acute respiratory distress syndrome

Abstract Background The open lung approach (OLA) reportedly has lung-protective effects against acute respiratory distress syndrome (ARDS). Recently, lowering of the driving pressure (ΔP), rather than improvement in lung aeration per se, has come to be considered as the primary lung-protective mecha...

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Bibliographic Details
Main Authors: Kentaro Tojo, Tasuku Yoshida, Takuya Yazawa, Takahisa Goto
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Critical Care
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13054-018-2154-2