Caspase-3 Cleaves Extracellular Vesicle Proteins During Auditory Brainstem Development

Caspase-3 Cleaves Extracellular Vesicle Proteins During Auditory Brainstem Development

Sound localization requires extremely precise development of auditory brainstem circuits, the molecular mechanisms of which are largely unknown. We previously demonstrated a novel requirement for non-apoptotic activity of the protease caspase-3 in chick auditory brainstem development. Here, we used...

Full description

Bibliographic Details
Main Authors: Forrest Weghorst, Yeva Mirzakhanyan, Kian Samimi, Mehron Dhillon, Melanie Barzik, Lisa L. Cunningham, Paul D. Gershon, Karina S. Cramer
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Cellular Neuroscience
Subjects:
auditory brainstem
neural development
caspase-3
non-apoptotic
extracellular vesicles
proteomics
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2020.573345/full

Internet

https://www.frontiersin.org/articles/10.3389/fncel.2020.573345/full

Similar Items