Salvianolic acid A promotes mitochondrial biogenesis and mitochondrial function in 3T3-L1 adipocytes through regulation of the AMPK-PGC1α signalling pathway

Salvianolic acid A promotes mitochondrial biogenesis and mitochondrial function in 3T3-L1 adipocytes through regulation of the AMPK-PGC1α signalling pathway

Mitochondrial dysfunction is associated with insulin resistance and type 2 diabetes (T2DM). Decreased mitochondrial abundance and function were found in white adipose tissue (WAT) of T2DM patients. Therefore, promoting WAT mitochondrial biogenesis and improving adipocyte metabolism may be strategies...

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Bibliographic Details
Main Authors: Jialin Sun, Ping Leng, Xiao Li, Qie Guo, Jun Zhao, Yu Liang, Xiaolei Zhang, Xue Yang, Jing Li
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Adipocyte
Subjects:
Salvianolic acid A
3T3-L1 adipocytes
mitochondrial biogenesis
mitochondrial function
AMPK
PGC-1α
Online Access:https://www.tandfonline.com/doi/10.1080/21623945.2022.2116790

Internet

https://www.tandfonline.com/doi/10.1080/21623945.2022.2116790

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