Avian retrovirus integrase-enhanced transgene integration into mammalian cell DNA in vivo

Systems for introducing DNA genes-of-interest into mammalian cellular genomes have ranged from the use of different physical techniques to viruses including retroviruses. We have developed a microinjection method for an efficient and permanent integration of a DNA transgene into the cell genome by u...

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Bibliographic Details
Main Authors: Aqing Yao, Roger Chiu, Ajaykumar Vora, David B. Brown, Duane Grandgenett, Brian R. Davis
Format: Article
Language:English
Published: Taylor & Francis Group 2003-11-01
Series:BioTechniques
Online Access:https://www.future-science.com/doi/10.2144/03355dd04