Anatomically resolved transcriptome and proteome landscapes reveal disease‐relevant molecular signatures and systematic changes in heart function of end‐stage dilated cardiomyopathy

Anatomically resolved transcriptome and proteome landscapes reveal disease‐relevant molecular signatures and systematic changes in heart function of end‐stage dilated cardiomyopathy

Abstract Dilated cardiomyopathy (DCM), as characterized by the left ventricular dilatation and contractile dysfunction, is one of the molecular mechanisms of which are largely unexplored. Here, we profiled the region‐resolved transcriptome and proteome of healthy and DCM human myocardial tissue and...

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Bibliographic Details
Main Authors: Ling Lin, Shanshan Liu, Zhangwei Chen, Yan Xia, Juanjuan Xie, Mingqiang Fu, Danbo Lu, Yuan Wu, Huali Shen, Pengyuan Yang, Juying Qian
Format: Article
Language:English
Published: Wiley 2023-02-01
Series:View
Subjects:
dilated cardiomyopathy, heart chambers
proteome, serum biomarker panel, transcriptome
Online Access:https://doi.org/10.1002/VIW.20220040

Internet

https://doi.org/10.1002/VIW.20220040

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