From the stomach to locus coeruleus: new neural substrate for ghrelin’s effects on ingestive, motivated and anxiety-like behaviors

From the stomach to locus coeruleus: new neural substrate for ghrelin’s effects on ingestive, motivated and anxiety-like behaviors

Ghrelin, a stomach-derived orexigenic hormone, has a well-established role in energy homeostasis, food reward, and emotionality. Noradrenergic neurons of the locus coeruleus (LC) are known to play an important role in arousal, emotion, cognition, but recently have also been implicated in control of...

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Bibliographic Details
Main Authors: Ivana Maric, Lorena López-Ferreras, Yashaswini Bhat, Mohammed Asker, Stina Börchers, Lauren Bellfy, Suyeun Byun, Janine L. Kwapis, Karolina P. Skibicka
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Pharmacology
Subjects:
ghrelin
hindbrain
locus coeruleus (LC)
food motivation
anxiety-like behavior
LEAP2
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1286805/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1286805/full

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