Intraperitoneal Injection of Human Ferritin Heavy Chain Attenuates the Atherosclerotic Process in APOE-Knockout Mice

Intraperitoneal Injection of Human Ferritin Heavy Chain Attenuates the Atherosclerotic Process in APOE-Knockout Mice

<b>Background:</b> Iron overload can accelerate the accumulation of lipid oxides and contribute to the progression of atherosclerosis. Ferritin heavy chain (FT-H) exhibits oxidase activity, which inhibits the toxicity of ferrous ions and reduces oxidative damage. We investigated the effe...

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Bibliographic Details
Main Authors: Wanzhong Yuan, Jianlin Zhang, Ran Huo, Chaofan Hou, Jun Yang, Tao Wang
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
ferritin heavy chain
atherosclerosis
transferrin receptor
iron
APOE-knockout mice
Online Access:https://www.mdpi.com/2308-3425/10/7/309

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https://www.mdpi.com/2308-3425/10/7/309

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