Decreased HLA-DQ expression on peripheral blood cells in children with varying number of beta cell autoantibodies

Decreased HLA-DQ expression on peripheral blood cells in children with varying number of beta cell autoantibodies

The risk for type 1 diabetes is strongly associated with HLA-DQ and the appearance of beta cell autoantibodies against either insulin, glutamate decarboxylase (GAD65), insulinoma-associated protein-2 (IA-2), or zinc transporter 8 (ZnT8). Prolonged exposure to autoantibodies may be related to T cell...

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Bibliographic Details
Main Authors: Agnes Andersson Svärd, Marlena Maziarz, Anita Ramelius, Markus Lundgren, Åke Lernmark, Helena Elding Larsson, C. Andersson, R. Bennet, I. Jönsson, M. Ask, J. Bremer, C. Brundin, C. Cilio, C. Hansson, G. Hansson, S. Ivarsson, B. Jonsdottir, B. Lindberg, B. Lernmark, J. Melin, A. Carlsson, E. Cedervall, B. Jönsson, K. Larsson, J. Neiderud
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Journal of Translational Autoimmunity
Subjects:
Autoimmunity
Type 1 diabetes
Autoantibodies
Human Leukocyte antigen
Cell surface imunofluorescence
Online Access:http://www.sciencedirect.com/science/article/pii/S2589909020300198

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http://www.sciencedirect.com/science/article/pii/S2589909020300198

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