Research progress on COX-2/PGE<sub>2</sub>/EP<sub>4</sub> signaling axis in colon cancer

Research progress on COX-2/PGE<sub>2</sub>/EP<sub>4</sub> signaling axis in colon cancer

The expression of cyclooxygenase 2 (COX-2) was up-regulated and prostaglandin E<sub>2</sub> (PGE<sub>2</sub>) was significantly increased in colon cancer patients. As the main prostaglandin produced by COX-2, PGE<sub>2</sub> plays an important role in angiogenesis...

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Bibliographic Details
Main Authors: ZHENG Lirong, DU Haoyang, ZHANG Ruifen, ZHANG Hairong, BAO Aruhan, YU Lei, CUI Hongwei
Format: Article
Language:zho
Published: The Editorial Department of Chinese Journal of Clinical Research 2023-09-01
Series:Zhongguo linchuang yanjiu
Subjects:
cyclooxygenase 2
prostaglandin e<sub>2</sub>
ep<sub>4</sub> receptor
colon cancer; aspirin; celecoxib
Online Access:http://zglcyj.ijournals.cn/zglcyj/ch/reader/view_abstract.aspx?file_no=20230912&flag=1

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http://zglcyj.ijournals.cn/zglcyj/ch/reader/view_abstract.aspx?file_no=20230912&flag=1

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