Resampling-based tests for Lasso in genome-wide association studies

Resampling-based tests for Lasso in genome-wide association studies

Abstract Background Genome-wide association studies involve detecting association between millions of genetic variants and a trait, which typically use univariate regression to test association between each single variant and the phenotype. Alternatively, Lasso penalized regression allows one to joi...

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Bibliographic Details
Main Authors: Jaron Arbet, Matt McGue, Snigdhansu Chatterjee, Saonli Basu
Format: Article
Language:English
Published: BMC 2017-07-01
Series:BMC Genetics
Subjects:
Lasso
GWAS
Resampling
Permutation
Bootstrap
Testing
Online Access:http://link.springer.com/article/10.1186/s12863-017-0533-3

Internet

http://link.springer.com/article/10.1186/s12863-017-0533-3

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