Lack of causal association between heart failure and osteoporosis: a Mendelian randomization study

Lack of causal association between heart failure and osteoporosis: a Mendelian randomization study

Abstract Objectives Heart failure (HF) has been implicated in osteoporosis. However, causality remains unestablished. Here, we sought to assess causal associations of genetic liability to HF with osteoporosis using Mendelian randomization (MR) analyses. Methods Independent single nucleotide polymorp...

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Bibliographic Details
Main Authors: Heng Chen, Runze Ye, Xiaogang Guo
Format: Article
Language:English
Published: BMC 2022-11-01
Series:BMC Medical Genomics
Subjects:
Mendelian randomization
Causal association
Heart failure
Osteoporosis
Bone mineral density
Fracture
Online Access:https://doi.org/10.1186/s12920-022-01385-8

Internet

https://doi.org/10.1186/s12920-022-01385-8

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