c-myc Amplification Is Frequent in Esophageal Adenocarcinoma and Correlated with the Upregulation of VEGF-A Expression

BACKGROUND: Deregulation of c-myc plays a major role in the carcinogenesis of human malignancies. We investigated the amplification of the c-myc gene in a surgical series of Barrett cancers. METHODS: Primary resected esophageal (Barrett) adenocarcinomas (n = 84) were investigated for c-myc amplifica...

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Bibliographic Details
Main Authors: Burkhard H.A. von Rahden, Hubert J. Stein, Franziska Pühringer-Oppermann, Mario Sarbia
Format: Article
Language:English
Published: Elsevier 2006-09-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558606800941