Optimizing clinico-genomic disease prediction across ancestries: a machine learning strategy with Pareto improvement

Abstract Background Accurate prediction of an individual’s predisposition to diseases is vital for preventive medicine and early intervention. Various statistical and machine learning models have been developed for disease prediction using clinico-genomic data. However, the accuracy of clinico-genom...

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Bibliographic Details
Main Authors: Yan Gao, Yan Cui
Format: Article
Language:English
Published: BMC 2024-06-01
Series:Genome Medicine
Subjects:
Online Access:https://doi.org/10.1186/s13073-024-01345-0