Priming mycobacterial ESX-secreted protein B to form a channel-like structure
ESX-1 is a major virulence factor of Mycobacterium tuberculosis, a secretion machinery directly involved in the survival of the microorganism from the immune system defence. It disrupts the phagosome membrane of the host cell through a contact-dependent mechanism. Recently, the structure of the inne...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-01-01
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Series: | Current Research in Structural Biology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2665928X21000118 |