Human Innate Immunity to <named-content content-type="genus-species">Toxoplasma gondii</named-content> Is Mediated by Host Caspase-1 and ASC and Parasite GRA15
ABSTRACT Interleukin-1β (IL-1β) functions as a key regulator of inflammation and innate immunity. The protozoan parasite Toxoplasma gondii actively infects human blood monocytes and induces the production of IL-1β; however, the host and parasite factors that mediate IL-1β production during T. gond...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
American Society for Microbiology
2013-08-01
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| Series: | mBio |
| Online Access: | https://journals.asm.org/doi/10.1128/mBio.00255-13 |