THYMOMA (REVIEW OF THE LITERATURE)

Objective. We aimed to systematically review the literature dealing with the epidemiology, classification, clinical course, diagnosis and treatment of thymoma. Material and methods. We reviewed retrospective and prospective randomized trials using Medline and Elibrary databases. Results. The classif...

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Dettagli Bibliografici
Autori principali: O. A. Alexandrov, A. B. Ryabov, O. V. Pikin
Natura: Articolo
Lingua:Russian
Pubblicazione: Russian Academy of Sciences, Tomsk National Research Medical Center 2017-09-01
Serie:Сибирский онкологический журнал
Soggetti:
Accesso online:https://www.siboncoj.ru/jour/article/view/572
Descrizione
Riassunto:Objective. We aimed to systematically review the literature dealing with the epidemiology, classification, clinical course, diagnosis and treatment of thymoma. Material and methods. We reviewed retrospective and prospective randomized trials using Medline and Elibrary databases. Results. The classification system, prognostic factors, paraneoplastic syndromes and their incidence in patients with thyoma were described. The diagnostic value of computed tomography, magnetic resonance imaging and positron emission tomography was evaluated and the methods of morphologic verification were described. The main attention was paid to multimodality treatment of thymoma, including surgery and intraoperative radiotherapy. Conclusion. Thymoma is a rare tumor. The accumulation of long-term follow-up results prompted the changes in clinical management of thymoma. Predisposition to late recurrence even after radical surgery determined multimodality treatment strategies.
ISSN:1814-4861
2312-3168