Correlating Basal Gene Expression across Chemical Sensitivity Data to Screen for Novel Synergistic Interactors of HDAC Inhibitors in Pancreatic Carcinoma

Correlating Basal Gene Expression across Chemical Sensitivity Data to Screen for Novel Synergistic Interactors of HDAC Inhibitors in Pancreatic Carcinoma

Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive and lethal malignancies. Development of the chemoresistance in the PDAC is one of the key contributors to the poor survival outcomes and the major reason for urgent development of novel pharmacological approaches in a treatment of...

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Bibliographic Details
Main Authors: Nemanja Djokovic, Ana Djuric, Dusan Ruzic, Tatjana Srdic-Rajic, Katarina Nikolic
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Pharmaceuticals
Subjects:
bioinformatics
PDAC
synergism
sphingolipid signaling
HDAC inhibitors
ROCK inhibitors
Online Access:https://www.mdpi.com/1424-8247/16/2/294

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https://www.mdpi.com/1424-8247/16/2/294

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