Mechanism of LolCDE as a molecular extruder of bacterial triacylated lipoproteins

In Gram-negative bacteria, lipoproteins are transported from the inner membrane (IM) to the outer membrane (OM) by the ATP-binding cassette (ABC) transporter LolCDE. Here the authors present cryo-EM structures of nanodisc-embedded LolCDE in different states, providing mechanistic insight into the tr...

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Bibliographic Details
Main Authors: Stuti Sharma, Ruoyu Zhou, Li Wan, Shan Feng, KangKang Song, Chen Xu, Yanyan Li, Maofu Liao
Format: Article
Language:English
Published: Nature Portfolio 2021-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-24965-1