Improved diagnosis of inflammatory bowel disease and prediction and monitoring of response to anti-TNF alpha treatment based on measurement of signal transduction pathway activity

Improved diagnosis of inflammatory bowel disease and prediction and monitoring of response to anti-TNF alpha treatment based on measurement of signal transduction pathway activity

Objective: Ulcerative colitis (UC) and Crohn’s disease (CD) are two subtypes of chronic inflammatory bowel disease (IBD). Differential diagnosis remains a challenge. Anti-TNFα treatment is an important treatment for IBD, yet resistance frequently occurs and cannot be predicted. Consequently, many pa...

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Bibliographic Details
Main Authors: Wilbert Bouwman, Wim Verhaegh, Anja van de Stolpe
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Pharmacology
Subjects:
ulcerative colitis
crohn’s disease
IBD
signal transduction pathway
treatment response
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.1008976/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.1008976/full

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