Glucocorticoid induces human beta cell dysfunction by involving riborepressor GAS5 LincRNA

Glucocorticoid induces human beta cell dysfunction by involving riborepressor GAS5 LincRNA

Objective: A widely recognized metabolic side effect of glucocorticoid (GC) therapy is steroid-induced diabetes mellitus (DM). However, studies on the molecular basis of GC-induced pancreatic beta cell dysfunction in human beta cells are lacking. The significance of non-coding RNAs in various cellul...

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Bibliographic Details
Main Authors: Jonathan L.S. Esguerra, Jones K. Ofori, Mototsugu Nagao, Yuki Shuto, Alexandros Karagiannopoulos, Joao Fadista, Hitoshi Sugihara, Leif Groop, Lena Eliasson
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:Molecular Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877819309640

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http://www.sciencedirect.com/science/article/pii/S2212877819309640

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