Deletion of Glut1 in early postnatal cartilage reprograms chondrocytes toward enhanced glutamine oxidation

Abstract Glucose metabolism is fundamental for the functions of all tissues, including cartilage. Despite the emerging evidence related to glucose metabolism in the regulation of prenatal cartilage development, little is known about the role of glucose metabolism and its biochemical basis in postnat...

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Bibliographic Details
Main Authors: Cuicui Wang, Jun Ying, Xiangfeng Niu, Xiaofei Li, Gary J. Patti, Jie Shen, Regis J. O’Keefe
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Bone Research
Online Access:https://doi.org/10.1038/s41413-021-00153-1