Detecting antibody reactivities in Phage ImmunoPrecipitation Sequencing data

Detecting antibody reactivities in Phage ImmunoPrecipitation Sequencing data

Abstract Phage ImmunoPrecipitation Sequencing (PhIP-Seq) is a recently developed technology to assess antibody reactivity, quantifying antibody binding towards hundreds of thousands of candidate epitopes. The output from PhIP-Seq experiments are read count matrices, similar to RNA-Seq data; however...

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Bibliographic Details
Main Authors: Athena Chen, Kai Kammers, H Benjamin Larman, Robert B. Scharpf, Ingo Ruczinski
Format: Article
Language:English
Published: BMC 2022-09-01
Series:BMC Genomics
Subjects:
Antobodies
Bayesian Model
Peptides
Phage ImmunoPrecipitation Sequencing
Reactivity
Online Access:https://doi.org/10.1186/s12864-022-08869-y

Internet

https://doi.org/10.1186/s12864-022-08869-y

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