Endothelial Progenitor Cell-Based in vitro Pre-Endothelialization of Human Cell-Derived Biomimetic Regenerative Matrices for Next-Generation Transcatheter Heart Valves Applications

Endothelial Progenitor Cell-Based in vitro Pre-Endothelialization of Human Cell-Derived Biomimetic Regenerative Matrices for Next-Generation Transcatheter Heart Valves Applications

Hemocompatibility of cardiovascular implants represents a major clinical challenge and, to date, optimal antithrombotic properties are lacking. Next-generation tissue-engineered heart valves (TEHVs) made from human-cell-derived tissue-engineered extracellular matrices (hTEMs) demonstrated their rece...

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Bibliographic Details
Main Authors: Sarah E. Motta, Polina Zaytseva, Emanuela S. Fioretta, Valentina Lintas, Christian Breymann, Simon P. Hoerstrup, Maximilian Y. Emmert
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
human cell-derived tissue-engineered matrices
endothelial colony forming cell
anti-coagulation
hemocomaptibility
scratch assay
HPL
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.867877/full

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https://www.frontiersin.org/articles/10.3389/fbioe.2022.867877/full

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