Regulation of Chk1

<p>Abstract</p> <p>Chk1 is a serine/threonine protein kinase that is the effector of the G2 DNA damage checkpoint. Chk1 homologs have a highly conserved N-terminal kinase domain, and a less conserved C-terminal regulatory domain of ~200 residues. In response to a variety of genomic...

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Bibliographic Details
Main Authors: Calonge Teresa M, Tapia-Alveal Claudia, O'Connell Matthew J
Format: Article
Language:English
Published: BMC 2009-04-01
Series:Cell Division
Online Access:http://www.celldiv.com/content/4/1/8